laeA — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G30404 (laeA) on chromosome 3 of Fusarium graminearum PH-1 encodes a protein containing a SAM-dependent methyltransferase superfamily domain and is annotated with methyltransferase activity. The gene is associated with regulation of secondary metabolism, secondary metabolite biosynthesis, activation of gliotoxin anabolism, ergosterol anabolism, spore formation, disruption of host phagocytosis, DNA-dependent transcription, and methylation. The encoded product localises to the nucleus. Studies of related genes in other species link the family to methyltransferase activity (EC 2.1.1.-).