CHS7 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G06553 (CHS7) on chromosome 1 of Fusarium graminearum PH-1 encodes a protein annotated with unfolded protein binding (GO:0051082). The gene is associated with cell wall biogenesis, chitin anabolism, cell wall organization, homologous recombination, protein folding, and protein transport, and its product localizes to the ER membrane. Phenotypic associations include abnormal cell wall morphology, decreased chitin deposition, absent filamentous and pseudohyphal growth, altered mating response and efficiency, increased sporulation efficiency, increased biofilm formation, altered mitotic recombination rates, increased viability, increased vegetative growth, and altered stress resistances (increased resistance to alkaline pH, acid pH, hyperosmotic stress, and hydrostatic pressure; decreased cold sensitivity and freeze-thaw resistance). Studies of related genes in other species link the CHS7 family to reduced virulence and decreased desiccation resistance.