AMD2 — Aspergillus nidulans FGSC A4

Summary

AnAMD2 (ANIA_10833) on chromosome 1 of Aspergillus nidulans FGSC A4 encodes an amidase-domain protein with fatty acid amide hydrolase, glutaminyl-tRNA synthase (glutamine-hydrolyzing), amidase, hydrolase, and ATP-binding activities. The gene is associated with glutaminyl-tRNAGln biosynthesis via transamidation, carbon catabolite repression, antibiotic anabolism, fatty acid breakdown, and mitochondrial translation. Its product localises to the glutamyl-tRNA(Gln) amidotransferase complex, mitochondria, cytoplasm, cytosol, and nucleus. Studies of related genes in other species link the family to glutamyl-tRNA(Gln) amidotransferase subunit A function, N-acylethanolamine amidohydrolase activity, and altered starvation resistance and chemical tolerance.