NUP — Aspergillus nidulans FGSC A4

Summary

ANIA_10683, symbol NUP and preferred name AnNUP on Aspergillus nidulans FGSC A4 chromosome 5, encodes a purine nucleoside permease belonging to the Pur_nuclsid_perm family. The gene product has purine nucleoside transmembrane transporter activity and nucleoside:proton symporter activity, and is associated with purine nucleoside membrane transport, nucleoside transport, and nucleoside metabolism. AnNUP is associated with interphase, mitotic exit, spindle assembly, anaphase, meiosis, mitosis, and chromosome division, as well as membrane transport. The protein localises to the ER and membrane. Studies of related genes in other species link the family to nucleoside phosphorylase superfamily domains, though these associations are not established for AnNUP itself.