URE1 — Aspergillus nidulans FGSC A4

Summary

ANIA_10079 (URE1) on chromosome 8 of Aspergillus nidulans FGSC A4 encodes a urease enzyme (EC 3.5.1.5) with urease activity and nickel binding, belonging to the urease alpha, beta, and gamma subunit families. The gene is associated with urea breakdown and localises to the urease complex and cytosol. Through related genes in other species, the family is linked to nitrogen content and reduced virulence, as well as to cryptococcosis and invasive pulmonary aspergillosis. The gene is also known by the symbols URE2 and AnURE1.