CP1 — Aspergillus nidulans FGSC A4

Summary

ANIA_10184 (CP1, AnCP1) on Aspergillus nidulans chromosome 8 encodes a serine carboxypeptidase (EC 3.4.16.6) belonging to the peptidase S10 and alpha/beta hydrolase families. The gene is associated with positive regulation of conidium formation, proteolysis, hyphal growth, intracellular transport, chromatin organization, regulation of gene expression, antibiotic and monocarboxylic acid anabolism, apoptotic processes, nitric oxide storage, methylation, and homeostasis. The encoded protein localizes to the trans-Golgi network. Associations with numerous phenotypes include altered cell death, autophagy, endocytosis, protein secretion, nuclear fusion during mating, prion inheritance, replicative lifespan, cytokinesis, and chemical compound accumulation. Studies of related genes in other species link the family to apoplastic effector function and floral organ identity traits.