CAT1 — Aspergillus nidulans FGSC A4

Summary

ANIA_09339 (CAT1, catB) encodes a catalase enzyme (EC 1.11.1.6) with catalase activity, heme binding, and metal binding, belonging to the clade 2 catalase family. In Aspergillus nidulans FGSC A4 on chromosome 8, this gene is associated with detoxification of hydrogen peroxide, cellular response to oxidative stress, and response to heat and iron ion starvation. It is linked to regulation of siderophore anabolism, ornithine metabolism, asexual reproduction and sporulation, conidia formation, appressorium formation, cell differentiation, and growth regulation. The protein localizes to the peroxisomal lumen, cytosol, ascospore wall, and extracellular. Studies of related genes in other species link the catalase family to oxidative stress response.