PYR4 — Aspergillus nidulans FGSC A4

Summary

AnPYR4 (PYR4) on chromosome 8 of Aspergillus nidulans FGSC A4 encodes a PaxB-like protein with lyase activity (EC 4.2.3.-). The gene is associated with aflatoxin metabolism and anabolism, terpenoid anabolism, asexual sporulation, spore formation, morphogenesis, regeneration, digestion, and DNA modification, integration, gene conversion, mitotic recombination, and homologous recombination. Its product is localized to the membrane. Studies of related genes in other species link the PaxB family to oxidative stress response, though this association is not established for AnPYR4 itself.