atnA — Aspergillus nidulans FGSC A4

Summary

ANIA_09243 (atnA) on Aspergillus nidulans chromosome 8 encodes a putative NRPS-like enzyme with ligase, isomerase, and phosphopantetheine binding activities. The gene is associated with nonribosomal peptide biosynthesis, amino acid activation for that process, and secondary metabolism, including sterigmatocystin and toxin biosynthesis. It is also linked to spore germination, sexual reproduction, and small molecule metabolism, with the product localised to the cytoplasm. Studies of related genes in other species connect the family to reduced virulence and fusarium head blight, though these associations are not established for atnA itself.