alcR — Aspergillus nidulans FGSC A4

Summary

ANIA_08978 (symbol alcR) on chromosome 7 of Aspergillus nidulans FGSC A4 encodes a Zn2Cys6 DNA-binding transcription factor of the AtrR-like family. The protein localises to the nucleus and has DNA-binding transcription factor activity. The gene is associated with carbon catabolite repression, the glucose effect, and catabolite repression, as well as with carbohydrate utilisation, including xylan breakdown. It is also linked to ethanol and acetaldehyde breakdown, acetate breakdown, threonine breakdown, and ethanol metabolism. Additional associations include secondary metabolism, siderophore transport, nuclear transport and import, heterotrophy, and IFNB production. Studies of related genes in other species link the family to ethanol-dependent gene regulation.