CBH1 — Aspergillus nidulans FGSC A4

Summary

ANIA_08717 (symbol CBH1, also known as AnCBH1 or CBP1) in Aspergillus nidulans FGSC A4 on chromosome 3 encodes a protein with a homeobox-like superfamily domain and a DDE superfamily endonuclease domain, and is annotated with centromere binding, sequence-specific DNA binding, and chromatin adaptor molecular functions. The gene is associated with negative regulation of rDNA heterochromatin formation, carbon catabolite repression, donor selection, and digestion. Its product localises to the condensed chromosome centric region, centromere complex, mating-type region heterochromatin, chromatin, and nucleus. Studies of related genes in other species link the family to centromere binding and DNA-binding activities, though these associations are not yet established for AnCBH1 itself.