niaD — Aspergillus nidulans FGSC A4

Summary

ANIA_08058 (symbol niaD) on chromosome 2 of Aspergillus nidulans FGSC A4 encodes a putative sulfite oxidase that also possesses nitrate reductase (NADPH) activity, moco binding, molybdenum ion binding, cytochrome-b5 reductase activity acting on NAD(P)H, FAD binding, heme binding, and redox activity. The gene is associated with nitrate assimilation, nitrate import, nitrogen utilization, response to hypoxia, anaerobic respiration, nitric oxide anabolism, arginine breakdown and its regulation, gibberellin biosynthesis, sulfur metabolism, ATP anabolism, DNA-mediated transformation, meiotic gene conversion, transposition, regeneration, digestion, and regulation of mRNA stability. It is linked to the trait molybdenum content and nitrate uptake. The product localizes to mitochondria. Studies of related genes in other species connect the family to nitrate reductase (EC 1.7.1.3) activity.