PSD2 — Aspergillus nidulans FGSC A4

Summary

ANIA_07989 (PSD2) on Aspergillus nidulans FGSC A4 chromosome 2 encodes a phosphatidylserine decarboxylase, a member of the PSD family with phosphatidylserine decarboxylase activity (EC 4.1.1.65) and also annotated for L-tryptophan decarboxylase activity, phospholipid binding, and metal binding. The gene is associated with phosphatidylserine, phosphatidylethanolamine, and phosphatidylcholine anabolism, as well as protein autoprocessing and psilocybin biosynthetic process. It is linked to filamentous growth in response to chemical, starvation, and biotic stimuli, and to biofilm formation. The product localizes to the Golgi stack and membrane, endosome membrane, fungal-type vacuole membrane, cell division site, mitochondria, and cytosol. PSD2 is also associated with quantum yield. Studies of related genes in other species link the family to additional decarboxylase activities.