YPT3 — Aspergillus nidulans FGSC A4

Summary

ANIA_00347 (YPT3) on chromosome 8 of Aspergillus nidulans FGSC A4 encodes a small GTPase of the Rab family, with GTPase activity and GTP binding. This gene is associated with a wide range of cellular processes, including primary growth, vesicle-mediated transport, endocytic recycling, mitotic cytokinesis, and ascospore assembly. It is linked to the regulation of intracellular protein transport and membrane addition at sites of cytokinesis. The encoded protein localises to transport vesicles, the recycling endosome, the Spitzenkörper, and the growing cell tip. Phenotypic associations include delayed vegetative growth, abnormal sporulation efficiency, decreased cell cycle progression, increased aneuploidy, and altered endocytosis.