GLIJ — Aspergillus nidulans FGSC A4

Summary

ANIA_00224 (symbol GLIJ, preferred name AnGLIJ) on chromosome 8 of Aspergillus nidulans FGSC A4 encodes a metallodipeptidase (EC 3.4.13.19) belonging to the Pept_M19 metal hydrolase family, with metal-binding and dipeptidase activity. The gene is associated with regulation of gliotoxin anabolism, kojic acid anabolism, mycotoxin anabolism, sulfur metabolism, proteolysis, secretion, and suppression by symbiont of host immune response. The product is localized to the membrane. Studies of related genes in other species link the family to dipeptidase activity, but these associations are not established for AnGLIJ itself.