BD — Aspergillus nidulans FGSC A4

Summary

ANIA_00182 (symbol BD, preferred name AnBD) on Aspergillus nidulans chromosome 8 encodes the small GTPase RasA, a member of the Ras-type family with GTPase activity and GTP binding, classified as EC 3.6.5.2. The gene is associated with Ras protein signal transduction, regulation of conidium formation, spore germination, hyphal growth, mating type switching, meiosis, mitosis, nuclear division, cell polarity establishment, morphogenesis, cell death, protein folding, protein synthesis, mycose catabolism, and interaction with host. The product localizes to the plasma membrane. Phenotypic associations include decreased vacuolar transport rate, absent bipolar budding, altered redox state, increased mating type switching, decreased entry into G0, absent osmotic and oxidative stress resistance, delayed nuclear export, abnormal pheromone production, increased protein transport, delayed telophase progression, absent prion inheritance, increased recovery from pheromone-induced cell cycle arrest, decreased budding rate, premature RNA and protein accumulation, decreased intracellular transport, decreased flocculation, and absent transposable element transposition.

Annotations

Chromosome
8
Related genes
YLL017W, YLL016W, TS(CGA)C, BD, RAS1, bd, RCE1, DBF2
GO terms
protein synthesis, Cell Growth, Cell Death, Protein Folding, Hyphal Growth, plasmalemma, meiosis, Mating
Publications
28357334, 28357333, 8196622, 19214209, 27840029, 9491072, 11779796, 22244335
Traits
RESISTANCE TO CHEMICALS: DECREASED, COMPETITIVE FITNESS: DECREASED, STRESS RESISTANCE: DECREASED, INVIABLE, RESISTANCE TO CHEMICALS: INCREASED, CELL CYCLE PROGRESSION: ABNORMAL, NUCLEAR POSITION: ABNORMAL, ENTRY INTO G0 (STATIONARY PHASE): INCREASED