catA — Aspergillus fumigatus

Summary

AFU6G03890 (catA, also known as CAT-1 or AfCAT-1) on Aspergillus fumigatus chromosome 6 encodes a clade 2 catalase with haem-binding and metal-binding properties, classified as EC 1.11.1.6. This gene is associated with detoxification of hydrogen peroxide, cellular response to oxidative stress and heat, the MAPK cascade, immune response, asexual sporulation, conidia formation, autolysis, secondary metabolism, D-amino acid metabolism, glutathione metabolism, and nucleotide anabolism and metabolism. It is linked to the oxidative stress response trait. The encoded product localises to the ascospore wall, peroxisomal lumen, cytosol, and extracellular space. Studies of related sequences in other fungi, including catR and homologues in Fusarium and Verticillium species, connect the family to germination rate.