abcB — Aspergillus fumigatus

Summary

AFU5G12720 (abcB) on chromosome 5 of Aspergillus fumigatus encodes a putative ABC multidrug transporter with ATP hydrolase and ATP-binding activities, belonging to the ABCC subfamily. The gene is associated with membrane transport, localisation to the fungal-type vacuole membrane and plasmalemma, and has been linked to hyphal growth, sporulation, and homologous recombination. Studies of related genes in other species connect the family to reduced virulence and fusarium head blight in cereal crops such as wheat, barley, and maize, though these associations are not yet established for this specific gene.