pep1 — Aspergillus fumigatus

Summary

AFU5G13300 (pep1) on chromosome 5 of Aspergillus fumigatus encodes an aspartic endopeptidase (EC 3.4.23.18) of the aspergillopepsin-like family, with a predicted extracellular localisation. The gene is associated with proteolysis, protein breakdown, digestion, and secretion. It has been connected to the related genes PEP1 and yap2. Related genes in other species, including aspergillopepsin-F and endothiapepsin, are linked to the family by sequence similarity, and sequence similarity extends to peptidases from plant pathogens such as Verticillium dahliae and Fusarium oxysporum pathovars.