crmA — Aspergillus fumigatus

Summary

AFU293_100515 (crmA) on Aspergillus fumigatus chromosome 3 encodes a protein with isocyanide synthase DIT1 and acyl carrier protein-like domains, annotated with aryl-aldehyde dehydrogenase (NADP+) and medium-chain fatty acid-CoA ligase activities, as well as ligase, transferase, isomerase and redox activities, ATP binding and phosphopantetheine binding. The gene is associated with fatty acid metabolism, secondary metabolism and amino acid anabolism. Studies of related genes in other species link the family to unaffected pathogenicity and to ear and stalk rot in maize, though these associations are not established for A. fumigatus.