prx1 — Aspergillus fumigatus

Summary

AFU293_100682 (symbol prx1) on Aspergillus fumigatus chromosome 6 encodes a member of the short-chain dehydrogenase/reductase (SDR) family, an oxidoreductase with redox activity. The gene is associated with several biological processes, including response to fungi, cellular response to farnesol, actin cytoskeleton organization, translation elongation, cytoskeleton organization, secondary metabolite biosynthesis, and terpenoid anabolism. It is also linked to the protein drtF, which centres on DRIM-7-ENE-11, and to oxidative stress response. Studies of related genes in other species connect the SDR family to further oxidoreductase activities, including EC 1.1.99.- and EC 1.1.-.-, though these associations are not yet established for prx1 itself.