prx1 — Aspergillus fumigatus

Summary

AFU293_100709 (symbol prx1) on Aspergillus fumigatus chromosome 3 encodes a protein belonging to the short-chain dehydrogenase/reductase (SDR) family, characterised by an NAD(P)-binding domain and annotated with redox activity and an EC 1.-.-.- classification. The gene is associated with several biological processes, including response to fungi, cellular response to farnesol, actin cytoskeleton organisation, translation elongation, secondary metabolite biosynthesis, and terpenoid anabolism. It has also been linked to oxidative stress response. Studies of related genes in other species connect the SDR family to oxidoreductase activity (EC 1.1.1.- and 1.1.99.-), though these associations are not yet established for prx1 itself.