ERG25 — Aspergillus fumigatus
Summary
AFU2G01160 (AfERG25, ERG25) encodes a putative C-4 methylsterol oxidase, a sterol desaturase-related enzyme with 4-methylsterol oxidase activity, iron binding, and redox activity. It is associated with demethylation, sterol homeostasis, sterol anabolism, ergosterol anabolism, and mating, and localizes to the endoplasmic reticulum membrane. Studies of related genes in other species link the family to C-4 methylsterol oxidase function (EC 1.14.18.9).
Annotations
- Chromosome
- 2
- Related genes
- ERG25
- GO terms
- ER membrane, 4-methylsterol oxidase activity, sterol anabolism, redox activity, Mating, iron binding, ergosterol anabolism, ER
- Publications
- PMID:16110826, PMID:23442154, PMID:20237561, PMID:18191972, PMID:16537923, PMID:15273122, PMID:17419877, PMID:15820985