abr2 — Aspergillus fumigatus

Summary

AFU1G15670 (symbol abr2) on chromosome 1 of Aspergillus fumigatus encodes a laccase TilA, a copper-containing oxidase with p-diphenol:oxygen oxidoreductase activity (EC 1.10.3.2). The gene is associated with pigment metabolism, L-phenylalanine breakdown, conidiophore development, pigmentation, pigment anabolism, (M)-viriditoxin anabolism, sexual reproduction, melanin anabolism, homologous recombination, sporulation, mating, and homeostasis. The encoded protein is localized to the membrane, cell bound, and extracellular space. Studies of related genes in other species link the family to EC 1.10.3.18 and to unaffected pathogenicity, as well as to associations with Fusarium species and fusarium head blight in barley.