CHS5 — Verticillium dahliae

Summary

VDAG_00420 (VdCHS5) on Verticillium dahliae chromosome DS572695 encodes a chitin synthase with chitin synthase activity (EC 2.4.1.16), also annotated for cytoskeletal motor activity, actin binding and ATP binding. The protein contains chitin synthase, myosin motor and cytochrome b5-like domains. VdCHS5 is associated with asexual sporulation, hyphal growth, fungal-type cell wall organization, morphogenesis and chitin biosynthesis. It localizes to the plasma membrane, cell tip, cell periphery, cross wall and myosin complex. The gene has been connected to vascular wilt disease and to Arabidopsis thaliana and Gossypium hirsutum. Studies of related genes in other species link the family to infection processes, including leaf anthracnose and stalk rot in maize, as well as invasive aspergillosis and phaeohyphomycosis.