CHS — Sorghum bicolor

Summary

SORBI_3005G135500 (CHS) on sorghum chromosome 5 encodes a protein with chalcone/stilbene synthase and polyketide synthase type-III domains, as well as a thiolase-like region. The enzyme exhibits naringenin-chalcone synthase, phloroisovalerophenone synthase, and bisdemethoxycurcumin synthase activities, along with acyltransferase and protein homodimerization functions. This gene is associated with chalcone, flavonoid, and polyketide biosynthesis, as well as secondary metabolism, pigmentation, pollen wall assembly, and UV protection. It is also linked to nitrogen fixation, nitric oxide storage, and response to UV-A. The product localizes to the cytoplasm. Studies of related genes in other species connect the family to additional flavonoid-related enzyme activities (EC 2.3.1.74, 2.3.1.156, 2.3.1.211).