CHS — Sorghum bicolor

Summary

SORBI_3005G135700 (CHS) on sorghum chromosome 5 encodes an uncharacterized protein with chalcone/stilbene synthase and polyketide synthase type-III domains. The enzyme exhibits naringenin-chalcone synthase, phloroisovalerophenone synthase, and bisdemethoxycurcumin synthase activities, along with acyltransferase and protein homodimerization functions. This gene is associated with flavonoid and polyketide biosynthesis, secondary metabolism, pigmentation, pollen wall assembly, nitrogen fixation, nitric oxide storage, and UV protection and response. The protein localizes to the endoplasmic reticulum and cytoplasm. Studies of related genes in other species link this family to EC 2.3.1.74, 2.3.1.156, and 2.3.1.211 activities.