CYP51 — Sorghum bicolor

Summary

SORBI_3005G132300 (CYP51) on sorghum chromosome 5 encodes an obtusifoliol 14-alpha demethylase, a cytochrome P450 enzyme with sterol 14-demethylase activity and multiple monooxygenase activities including beta-amyrin 11-oxidase and ent-kaurenoic acid monooxygenase. This gene is associated with sterol metabolism and biosynthesis, brassinosteroid biosynthesis and homeostasis, gibberellin metabolism and biosynthesis, triterpenoid and saponin metabolism and biosynthesis, pentacyclic triterpenoid metabolism, indole alkaloid metabolism, demethylation, and digestion. It is linked to pollen tube development, pollen germination, and pollen tube growth. The encoded protein localizes to the endoplasmic reticulum membrane and intracellular membrane-bounded organelles. Studies of related genes in other species link the CYP51 family to growth stage traits.