MYB3 — Nicotiana attenuata

Summary

A4A49_19615 (MYB3/MYB4) on chromosome 2 of coyote tobacco (Nicotiana attenuata) encodes a plant Myb-domain transcription factor with DNA-binding, protein-dimerization, small GTPase-binding and protein phosphatase activities. The gene is associated with the regulation of specialized metabolite biosynthesis, including phenylpropanoid, flavonoid, anthocyanin, proanthocyanidin and cinnamic acid pathways, as well as polyamine metabolism and sinapate ester downregulation. It is linked to herbivore resistance and anti-herbivore defence, trichome differentiation and spacing, oviposition, iron starvation response, and cell development. Localisation evidence places the product in the nucleus, cytoplasm and root hairs. Associations also connect the gene to leaf trichome density, UV-B sensitivity, jasmonic acid and brassinosteroid content, flowering time, seed and embryo development, root meristem development, osmotic and oxidative stress responses, and disease tolerance.