CAD — Nicotiana attenuata

Summary

A4A49_19826 (CAD) in coyote tobacco (Nicotiana attenuata) on scaffold01313 encodes a CAD-like protein with cinnamyl-alcohol dehydrogenase, geraniol dehydrogenase, vomilenine reductase, mannitol dehydrogenase, and 8-hydroxygeraniol dehydrogenase activities, along with zinc-binding and NAD(P)-dependent oxidoreductase activity. The gene is associated with phenylpropanoid, alkaloid, flavonoid, and lignin anabolism, as well as primary and carbohydrate metabolism, glycan biosynthesis, photorespiration, detoxification, and pigmentation. It is linked to oviposition and chewing, and to traits including lignin content, starch mobilization, and stem borer resistance. The encoded protein localizes to the cytoplasm. Studies of related genes in other species connect the family to cinnamyl-alcohol dehydrogenase (EC 1.1.1.195) and geraniol dehydrogenase (EC 1.1.1.183) activities, and to rice stem borer response traits.