CAD — Nicotiana attenuata

Summary

A4A49_19828 (CAD) in coyote tobacco (Nicotiana attenuata) on scaffold01313 encodes a CAD-like protein with cinnamyl-alcohol dehydrogenase, geraniol dehydrogenase, vomilenine reductase, mannitol dehydrogenase, and 8-hydroxygeraniol dehydrogenase activities, along with broader oxidoreductase activity acting on CH-OH groups with NAD or NADP as acceptor and zinc binding. The gene is associated with oviposition, glycan biosynthesis, primary metabolism, pigmentation, phenylpropanoid metabolism, photorespiration, detoxification, lignin anabolism, flavonoid anabolism, alkaloid metabolism, and carbohydrate metabolism, and its product localizes to the cytoplasm. It has been connected to starch mobilization and lignin content. Studies of related genes in other species link the family to alcohol dehydrogenase 9, ELI3, mannitol dehydrogenase, CAD1, geraniol dehydrogenase, vomilenine reductase, and 10-hydroxygeraniol oxidoreductase, with EC numbers including 1.1.1.183, 1.5.1.32, 1.1.1.324, 1.1.1.255, 1.1.1.195, and 1.3.1.-.