TPI — Nicotiana attenuata

Summary

A4A49_18354 (TPI) in coyote tobacco (Nicotiana attenuata) encodes a triose-phosphate isomerase, an enzyme with triose-phosphate isomerase activity (EC 5.3.1.1) that also binds copper. The gene is associated with core metabolic processes including glycolysis, gluconeogenesis, the Calvin cycle, glyceraldehyde-3-phosphate anabolism, and glycerol breakdown. It is associated with herbivore defense and resistance, aphid response, egg deposition, chewing, and oviposition, as well as with ethylene anabolism, secondary metabolism, metabolic burst, and virus-induced PTGS. Associations also include photosynthetic rate, protein content, fitness, nectar protein accumulation, and autophagy regulation. The product localises to the cytosol, chloroplast stroma, mitochondria, apoplast, plant-type cell wall, vacuole, plasmodesma, and plasmalemma. Studies of related genes in other species connect the family to carbon and sugar metabolism, male fertility, and combined stress tolerance.