ro-3 — Neurospora crassa

Summary

NCU03483, designated ro-3 in Neurospora crassa on chromosome 2, encodes a protein containing a CAP-Gly domain. The gene product is associated with the dynactin and dynein complexes and localises to the nucleus leading edge, cortical microtubule plus-ends, the spindle, and the actin and microtubule cytoskeletons. Annotated biological process terms link ro-3 to actin filament-based movement, nuclear congression, hyphal growth, mitotic spindle orientation, vesicle transport, and meiosis I. Studies of related genes in other species connect the family to dynactin function, though these associations are not yet established in N. crassa.