cyt-18 — Neurospora crassa

Summary

NCU03030, symbol cyt-18 on Neurospora crassa chromosome 1, encodes a tyrosine-tRNA ligase (TyrRS) with tyrosine-tRNA ligase activity (EC 6.1.1.1). The product belongs to the Tyr-tRNA-ligase family and possesses identical protein binding, RNA binding, and ATP binding activities. It is associated with tyrosyl-tRNA aminoacylation, tRNA charging, and protein synthesis, as well as mitochondrial translation and localisation to the mitochondrial lumen, mitochondria, and cytosol. The gene is linked to positive regulation of RNA splicing, group I intron splicing, RNA folding, mRNA processing, transposition, and digestion.