LREB — Neurospora crassa

Summary

NCU00902 (LREB, wc-2) on Neurospora crassa chromosome 1 encodes a protein with PAS and GATA zinc-finger domains, possessing photoreceptor activity, sequence-specific DNA binding, and transcription cis-regulatory region binding. It is associated with circadian rhythm and behavior, phototropism, photomorphogenesis, blue light response, phototransduction, and rhythmic processes. The gene is linked to carotenoid, siderophore, and pigment anabolism, reactive oxygen species anabolism, glycogen metabolism, asexual sporulation, regulation of growth, protein dephosphorylation, DNA metabolism, nuclear transport, and cellular localization. It localizes to both cytoplasm and nucleus. Associations with red light sensitivity and respiration rate have also been noted. Studies of related genes in other species link the family to reduced virulence.