C4H — Lactuca sativa

Summary

LsC4H, the garden lettuce gene on chromosome 8, encodes a trans-cinnamate 4-monooxygenase, a cytochrome P450 enzyme that binds iron and heme. This gene is associated with lignin metabolism, phenylpropanoid anabolism, flavonoid anabolism, terpenoid anabolism, and ubiquinone anabolism, and with response to wounding and response to light stimulus. It is linked to developmental process, pollen development, male fertility, and plant growth. Associations with root length, lateral root development, adventitious root development, auxin transport, Casparian strip formation, and UV-B protection have also been observed. The encoded protein localizes to the endoplasmic reticulum, plasma membrane, nucleus, and other cellular compartments. Studies of related genes in other species link them to lignification, dwarfism, altered phenylpropanoid metabolism, and abiotic stress adaptation.