PNH — Lactuca sativa

Summary

LsPNH, located on chromosome 8 of garden lettuce (Lactuca sativa), encodes a protein with Argonaute, Piwi, and PAZ domains, and is annotated with RNA endonuclease, siRNA binding, and dsRNA binding activities, as well as histone ubiquitin ligase and deubiquitinase activities. The gene is associated with miRNA and siRNA metabolic processes, gene silencing, and the regulation of development, including somatic stem cell population maintenance and cell fate commitment. It has been linked to numerous traits such as leaf morphology, polarity, and shattering, flower and inflorescence development, root phototropism, UV light sensitivity, photosynthetic ability, and metabolite content. Associations with seed dormancy, longevity, germination time, and auxin signalling have also been noted. Studies of related genes in other species connect the family to leaf shape, viral resistance, reproductive development, and heat tolerance.