ANS — Lactuca sativa

Summary

LsANS (LSAT_V11C800394300) on chromosome 8 of garden lettuce encodes a 2-oxoglutarate-dependent dioxygenase with leucocyanidin oxygenase, flavonol synthase, and jasmonic acid hydrolase activities. The gene is associated with anthocyanin, flavonoid, and pigment accumulation, as well as the regulation of jasmonic acid-mediated signaling and defense responses to insects, fungi, and oomycetes. It is linked to leaf color, anthocyanin and flavonoid content, chlorophyll content, photosynthetic rate, stomatal resistance, plant width, and shoot dry weight. Associations also include biotic and drought stress tolerance, spider mite resistance, oxidative stress, and pattern-triggered immunity. The protein localizes to the cytosol and cytoplasm. Studies of related genes in other species connect the family to jasmonic acid response, disease resistance, and pigment biosynthesis.