TMT — Lactuca sativa

Summary

LsTMT, encoded by gene LSAT_V11C800398430 on lettuce chromosome 8, is a SAM-dependent methyltransferase belonging to the gamma-tocopherol methyltransferase (γ-TMT) family. The enzyme exhibits tocopherol C-methyltransferase and N-methyltransferase activities. In lettuce, LsTMT is associated with vitamin E and alkaloid biosynthesis, particularly vindoline and general secondary metabolism. The protein localizes to multiple cellular compartments including the chloroplast inner membrane, thylakoid, tonoplast, vacuolar membrane, cytosol, and nucleus. LsTMT is associated with salt stress response, alpha-tocopherol biosynthesis, resistance to Botrytis cinerea, cold adaptation, glucose homeostasis, sugar transport, 5-methyl-PC-8 accumulation, sugar compartmentation, jasmonate accumulation, uranium stress tolerance, tocopherol biosynthesis, salt stress tolerance, growth rate, seed yield, oxidative stress tolerance, nitric oxide stress response, and tocopherol composition. Additionally, related genes in other species are associated with fructose content, total soluble sugar content, relative growth rate, sucrose content, quantum yield, seed yield trait, carotenoid content, sugar content, protein content, jasmonic acid content, low temperature stress response, plant height, oxidative stress response, plant growth and development trait, SALTTL, vitamin E content, seed tocopherol content, alpha-tocopherol accumulation, tocochromanol biosynthesis, plant development, alpha