WRKY3 — Lactuca sativa

Summary

LsWRKY3 (WRKY3) on chromosome 8 of garden lettuce encodes a WRKY domain-containing transcription factor with sequence-specific DNA binding, transcription cis-regulatory region binding, and protein homodimerization activity. It is associated with the regulation of antifungal innate immune responses, defence responses to fungi, and inhibition of defence response to bacteria. The gene is linked to abscisic acid anabolism and signalling involved in stomatal movement, positive regulation of leaf senescence, and responses to jasmonic acid, salicylic acid, chitin, and gibberellin. Associations with plant height, abscisic acid sensitivity, salt tolerance, and oxidative stress response have been noted. Related genes in other species link the family to salt stress tolerance and methyl jasmonate stress tolerance, and to resistance to necrotrophic pathogens and herbivores.