APX — Lactuca sativa

Summary

LsAPX (APX) on chromosome 8 of garden lettuce encodes a haem peroxidase of the Ccp1-like family, with annotated L-ascorbate peroxidase activity, p-coumarate 3-hydroxylase activity, and multiple additional molecular functions including heme binding, kinase activity, and siRNA binding. The gene is associated with cellular response to oxidative stress, photoprotection, auxin metabolism, cell cycle regulation, and leaf patterning. It has been linked to traits including leaf chlorophyll content, bacterial blight disease resistance, aphid response, flavonoid content, seed viability, days to flowering, photosynthetic rate, transpiration rate, and stomatal complex closure time. The gene product localises to the peroxisome membrane, chloroplast thylakoid membrane, stress granule, plasmodesma, and extracellular region. Related genes in other species connect the family to heat, drought, salt, and high-light stress tolerance, oxidative stress resistance, leaf senescence, and pathogen defence.