CYP71D4 — Lactuca sativa

Summary

LsCYP71D4 (CYP71D4) on chromosome 7 of garden lettuce (Lactuca sativa) encodes a cytochrome P450 monooxygenase with germacrene A acid 8beta-hydroxylase, costunolide synthase and germacrene A hydroxylase activities. The enzyme binds iron and heme, localises to the membrane, and is associated with sesquiterpenoid and lactone biosynthesis, the MVA pathway, fermentation, terpenoid and phenylpropanoid anabolism, and response to jasmonic acid. The gene has been linked to leaf weight. Related genes in other species connect the family to additional oxidoreductase activities (EC 1.14.14.170, 1.14.14.168, 1.14.14.150, 1.14.14.95, 1.14.14.151).

Annotations

Chromosome
7
Related genes
CYP71D55, CYP71D7, CYP71D4
GO terms
taste, lactone anabolism, lactone metabolism, sesquiterpenoid metabolism, Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Sesquiterpene Biosynthetic Process, phenylpropanoid anabolism, terpenoid anabolism
Publications
PMID:29758164, PMID:21858047, PMID:36582649, PMID:35723427, PMID:37036799, PMID:21515683, PMID:27625674, PMID:36105709
Traits
leaf weight