CYP71D4 — Lactuca sativa

Summary

LsCYP71D4 (CYP71D4) on lettuce chromosome 7 encodes a cytochrome P450 monooxygenase with germacrene A acid 8β-hydroxylase, costunolide synthase, and germacrene A hydroxylase activities, and binds heme and iron. It is associated with sesquiterpenoid and lactone biosynthesis, terpenoid and phenylpropanoid anabolism, and response to jasmonic acid, and localises to the endoplasmic reticulum membrane. Related genes in other species link the family to additional sesquiterpene oxidations and, distantly, to leaf weight, though these associations are not established in lettuce.

Annotations

Chromosome
7
Related genes
CYP71D55, CYP71D7, CYP71D4
GO terms
lactone anabolism, lactone metabolism, sesquiterpenoid metabolism, Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Sesquiterpene Biosynthetic Process, phenylpropanoid anabolism, terpenoid anabolism, Response To Jasmonic Acid
Publications
PMID:29758164, PMID:21858047, PMID:36582649, PMID:35723427, PMID:37036799, PMID:21515683, PMID:27625674, PMID:36105709
Traits
leaf weight