HMA1 — Lactuca sativa

Summary

LsHMA1, encoded by the gene LSAT_V11C700364980 on lettuce chromosome 7, is a P-type ATPase of the IB subfamily, annotated with copper, zinc, cadmium, potassium, and sodium transporter activities. It is associated with detoxification of zinc, copper, and cadmium ions, copper and iron ion membrane transport, cellular copper and zinc homeostasis, proton export, cell pH regulation, and response to toxic substances and cobalt ions. The gene is linked to traits including copper sensitivity, bacterial disease response, drought tolerance, high temperature stress response, oxidative stress response, leaf morphology, root development, plant height, flowering time, germination rate, and stomatal opening and closure. Related genes in other species connect the family to copper transport, photosensitivity under high light, the water-water cycle of photosynthesis, and cadmium and zinc translocation and detoxification.