HSP70 — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.6HG0608780 (HvHSP70) on barley chromosome 6H encodes a member of the Hsp70 family, a heat shock 70 kDa protein with ATP hydrolase activity, ATP-dependent protein folding chaperone function, and adenyl-nucleotide exchange factor activity. The gene is associated with protein folding in the endoplasmic reticulum, the ERAD pathway, the unfolded protein response, and protein refolding. It is associated with responses to heat, stress, viruses, and innate immunity, as well as pollen tube growth and lipid metabolism. Associations with thermotolerance, heat stress response, wound response, and photosynthetic rate have been observed. The encoded protein localises to the ER lumen, ER chaperone complex, chloroplast membrane, tonoplast, and Golgi complex. Studies of related genes in other species connect the family to grain yield, grain shape and width, spikelet fertility, heat tolerance, water use efficiency, and responses to stem rust and stripe rust.