OSD — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_00472 (symbol OSD) on chromosome 1 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a short-chain dehydrogenase/reductase (SDR family) with NAD(P)-binding domain, exhibiting (3S)-3-hydroxyacyl-CoA dehydrogenase, tetrahydroxynaphthalene reductase, and versicolorin reductase activities. The gene is associated with melanin, aflatoxin, and sterigmatocystin biosynthesis, as well as fatty acid metabolism, and its product localises to both the cytosol and nucleus. Related genes in other species link the SDR family to tetrahydroxynaphthalene reductase and versicolorin reductase functions (EC 1.1.1.252, 1.3.1.-).

Annotations

Chromosome
1
GO terms
Nucleus, Cytosol, (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity, redox activity, fatty acid metabolism, Oxidoreductase Activity, Acting On CH-OH Group Of Donors, aflatoxin anabolism, melanin anabolism
Publications
PMID:26266881, PMID:7486998, PMID:9680223, PMID:10618248, PMID:8017929, PMID:8999832, PMID:19146970, PMID:25368161