C4H — Arabidopsis thaliana

Summary

AT2G30490 (C4H, also known as CYP73A5) encodes cinnamate 4-hydroxylase, a cytochrome P450 enzyme. This gene is associated with lignin biosynthesis and deposition, monolignol production, and the formation of the Casparian strip diffusion barrier. C4H has been linked to plant dwarfism, reduced stature, altered phenylpropanoid metabolism, and male fertility. It is also associated with abiotic stress adaptation, UV-B protection, wound response, and anthocyanin and flavonoid content. The protein localises to the endoplasmic reticulum and is associated with suberin biosynthesis, auxin and gibberellin metabolism, and tracheary element differentiation. Studies of related genes in other species link the family to lignin content, fruit colour, and stress resistance.

Annotations

Chromosome
2
GO terms
homeostasis, NO storage, Digestion, iron binding, Seedling Development, Pollen Development, Plant-type Vacuole, innate immunity
Publications
30250509, 23383346, 23136168, 23140549, 19656330, 32265529, 31143367, 26079287
Traits
resveratrol production, abiotic stress adaptation, wound response, lignification, phenylpropanoid biosynthesis, cinnamate 4-hydroxylase activity, Dwarf, Reduced Apical Dominance, Altered Phenylpropanoid Metabolism, Stunted Plants, Reduced Stature