VAR2 — Arabidopsis thaliana

Summary

AT2G30950 (VAR2, also known as AtFtsH2) encodes a protein with peptidase M41 and AAA+ ATPase domains, annotated with metalloendopeptidase, protease, and ATP hydrolase activities as well as protein complex and chaperone binding. VAR2 is associated with photosystem II assembly, chloroplast thylakoid membrane localisation, plastid gene expression, chlororespiration, and protein quality control. The gene is linked to variegated leaf phenotype, leaf chlorosis, plant size, seed size, silique morphology, herbicide sensitivity, high temperature stress response, and heterosis. It has also been connected to auxin content, nitrate uptake, brassinosteroid sensitivity, ethylene sensitivity, and zinc sensitivity. Studies of related genes in other species link it to chloroplast biogenesis, leaf senescence, oxidative stress response, and thermomemory.