CLO3 — Arabidopsis thaliana

Summary

AT2G33380 (CLO3, also known as RD20) encodes a caleosin-related protein with linoleic acid epoxygenase activity, plant seed peroxygenase activity, heme oxygenase activity, and calcium ion binding, and is classified under EC 1.11.2.3. In Arabidopsis thaliana, CLO3 is associated with drought tolerance, salt stress response, and oxidative stress response, as well as with stomatal opening, transpiration rate, and flowering time. The gene is linked to lipid metabolism, including oxylipin metabolism, lipid storage, and negative regulation of lipid storage, and localizes to oil bodies, the endoplasmic reticulum, chloroplast membranes, and the nucleus. CLO3 is also connected to seed dormancy, seed maturation, disease tolerance, and fungal resistance. Studies of related genes in other species link the family to lipid accumulation and fatty acid content.