PHB — Arabidopsis thaliana

Summary

AT2G34710, known as PHABULOSA (PHB) or ATHB14, encodes a protein containing HD-Zip_III, START, and MEKHLA domains. The protein localises to the nucleus and cytosol, and is annotated with DNA binding, DNA-binding transcription factor activity, transcription cis-regulatory region binding, protein dimerization activity, identical protein binding, protein binding, and lipid binding. PHB is associated with specification of adaxial/abaxial axis polarity, determination of bilateral symmetry, leaf shaping, vasculature development, ground tissue patterning, SAM development, meristem initiation, and response to activity. It is linked to traits including leaf morphology, cotyledon morphology, floral organ identity, anther morphology, gynoecium development, root meristem development, seed maturation, and auxin, cytokinin, brassinosteroid, jasmonic acid, and high temperature stress sensitivity. Phenotypes observed for this gene include altered leaf polarity with adaxialized surfaces and ectopic shoot meristems (PHB-1D), and tri-cotyledons, enlarged SAM, stem fasciation, floral defects, and reduced fertility (PHB-13).